Review of Oncotarget Medical Journal and E-cigarettes Causing Gum Tissue Damage

Oncortarget can be described as a weekly open access medical journal that is usually peer-reviewed and covers research on the various aspects touching on oncology. It was founded in the year 2010 and Impact Journals publishes it. Oncortarget has two editors-in-chief, Andrei V. Gudkov and Mikhail Blagosklonny, who are both based at Roswell Park Cancer Institute. The journal’s 2015 impact factor stands at 5.0008 (according to Journal Citation Reports).

Study Published on Oncotarget about E-cigarettes causing damage to gum tissues

Electronic cigarettes (E-cigarettes) have for the longest time been marketed as the safer alternative compared to the conventional cigarettes. However, according to a new research published on Oncotarget medical journal, vaping could also be harmful to the gum tissues just like the ordinary cigarettes. The damage may lead to a number of oral health issues like tooth loss, gum diseases and mouth cancer according to Oncotarget.

How is it Possible?

E-cigarettes on are devices that are operated by batteries and they contain a cartridge that contains a liquid solution and a heating device. In a normal operating mode, the heating device heats the liquid thereby vaporizing it. The user then “puffs” on the device like they would do a conventional cigarette and inhale the resulting vapor. The e-cigarette does not contain tobacco which is the harmful component found in cigarettes. However, it contains nicotine and various chemicals including the flavoring components. These chemicals and the flavorings in particular cause damage to the mouth cells.

The Study

Irfan Rahman PhD., the professor of medicine at UR School of Dentistry and Medicine, led the study on e-cigarettes causing damages to the mouth cells. The electronic cigarettes have in the recent past continued to become popular especially among the younger adults and former smokers. Scientists in the past concluded that only the chemicals found in conventional cigarettes smoke posed a danger to the mouth cells. However, there is an increasing scientific data that seems to suggest otherwise and this study adds fuel to such claims at

According to Rahman, the study revealed that when an e-cigarette is burned, its resultant vapor causes the mouth cells to release their inflammatory proteins on This in turn increases the stress inside the cells causing damage to them. However, the damage caused is determined by the magnitude of smoking the e-cigarettes. The study also concluded that the chemicals used in the manufacture of the various flavors play a significant role in the damage of mouth cells.